The Washington Huskies take on the USC Trojans in Los Angeles, CA. Tip-off is set for 10:30 p.m. ET on Big Ten Network.
USC is favored by 6.5 points on the spread with a moneyline of -310. The total is set at 150.5 points.
Here’s my Washington vs. USC predictions and college basketball picks for March 5, 2025.
Washington vs USC Prediction
My Pick: USC -8 or Better
My Washington vs USC best bet is on the Trojans spread, with the best odds currently available at DraftKings. For all of your college basketball bets, find the best lines using our live NCAAB odds page.
Washington vs USC Odds
| Washington Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+6.5 -108 | 150.5 -112o / -108u | +250 |
| USC Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-6.5 -112 | 150.5 -112o / -108u | -310 |
- Washington vs USC spread: USC -6.5
- Washington vs USC over/under: 150.5 points
- Washington vs USC moneyline: USC -310, Washington +250
- Washington vs USC best bet: USC -8 or Better
Spread
I'm laying the points with the Trojans.
Moneyline
I'm passing on the moneyline.
Over/Under
I'm passing on the over/under.
My Pick: USC -8 or Better
Washington vs USC College Basketball Betting Preview
While USC has lost five straight games, I still think the Trojans' offense has trended up as the season has progressed.
Eric Musselman has messed with the lineups plenty, but the Desmond Claude-Wesley Yates III-Chibuzo Agbo-Saint Thomas-Rashaun Agee starting five has pieced together a respectable 119 Offensive Rating.
Although they lack spacing and shooting, the Trojans have become a good dribble offense (.90 pick-and-roll ball-handler PPP, 90th percentile, per Synergy).
Claude and Yates are excellent in that department, and the team is especially deadly in the mid-range (44% shooting on over eight attempts per game, 97th percentile, per CBB Analytics).
That feels like a good formula against Washington’s lackluster drop-coverage defense that funnels on-ball creation into the middle of the court and doesn’t do much to stop it (.82 pick-and-roll ball-handler PPP allowed, 35th percentile, per Synergy).
Washington parks Great Osobor at the rim, sticks on perimeter shooters and hands opposing ball-handlers lanes. However, the Huskies’ interior defense has regressed significantly since the Franck Kepnang injury, so they’re lifeless across the interior.
Unsurprisingly, the Trojans dropped 85 points in the first head-to-head meeting by shooting a ridiculous 25-for-34 (74%) from the interior. And they had no issues winning off the dribble (26 points on 24 ball-screens, 1.08 PPP, per Synergy).
