Bills vs Seahawks Prediction, Picks, Odds, Best Bets for NFL Week 8

Bills vs Seahawks Prediction, Picks, Odds, Best Bets for NFL Week 8 article feature image
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Action Network/Getty Images. Pictured: Josh Allen (left) and Geno Smith.

Starting soon
Odds Updating Soon
Matchup - 10/27 8:05pm UTCSpreadTotalMoneyline
-3-110
o45.5-105
-170
+3-110
u45.5-105
+142

The Buffalo Bills (5-2) and Seattle Seahawks (4-3) will kick off the Sunday afternoon slate of NFL Week 8. Kickoff is set for 4:05 p.m. ET from Lumen Field in Seattle. The game will be broadcast on FOX and can be streamed on platforms like YouTube TV.

The Bills are consensus 3-point favorites over the Seahawks (Bills -3) with the game total set at 45.5. Buffalo is -161 on the moneyline to win outright, while Seattle is +135 to pull off the upset.

Buffalo won 34-10 over the Titans last week. Josh Allen threw for 323 yards and 2 touchdowns, and Buffalo outscored Tennessee 27-0 in the second half. The Seahawks won 34-14 over the Falcons. Geno Smith threw for 2 touchdowns but will be without DK Metcalf, who left the game with an injury and will be out this week.

Let's get into my Bills vs. Seahawks predictions and my NFL picks for Sunday Week 8.


Buffalo Bills vs. Seattle Seahawks

Bills Logo
Sunday, Oct 27
4:05 p.m. ET
FOX
Seahawks Logo
Bills Odds
SpreadTotalMoneyline
-3
-110
45.5
-110o / -110u
-160
Seahawks Odds
SpreadTotalMoneyline
+3
-110
45.5
-110o / -110u
+135
Odds via bet365. Get up-to-the-minute NFL odds here.
bet365 Logo
  • Bills vs. Seahawks spread: Bills -3
  • Bills vs. Seahawks over/under: 45.5 points
  • Bills vs. Seahawks moneyline: Bills -161, Seahawks +135
  • Bills vs. Seahawks pick: Seahawks +3 & Under 45.5

My Seahawks vs. Bills best bet is on the under. For all of your NFL bets, be sure to find the best lines by using our live NFL odds page.

Pick Against the Spread

The Bills are 5-2 overall and 4-3 against the spread (ATS), while the Seahawks are 4-3 but just 2-4-1 against the number.

We have an Action PRO trend that indicates this is a spot to fade the Bills against a Seahawks team that is likely due for some positive regression against the spread.

Over/Under Prediction

Using the Action Network Luck Rankings, the under was the play here. The high winds in the forecast for Sunday in Seattle will help the under's cause, as well. However, I was on this at Under 47, and it is now down to 45. I'd still bet this based on the trends, but just know you're not getting the best of the number anymore.

Moneyline

Our systems do not recommend a play on the moneyline here.

My picks: Seahawks +3 & Under 45.5

How to Bet Bills vs. Seahawks Picks and Odds

Both teams are coming off blowout wins last week, with the Bills winning by 24 over the Titans and the Seahawks impressing with a 20-point win on the road against the Falcons. Seattle needed that win, having lost three straight by at least nine points, the last two of which were at home. Buffalo leads the AFC East at 5-2 and has covered in four of its last six games.

If you’re into betting luck and regression, then here are two picks: Seahawks +3 and the under.

One of our NFL PRO Systems in Action Labs popped with a play on Seattle against the spread – or should I say, a fade of Buffalo?

The Bills are unfortunately a match for a trend labeled “Fade Covering Teams.” If teams covering the spread by more than five points per game play a team with a winning percentage below 60%, the team which is outperforming market expectations only covers the spread 44% of the time. This trend activates in Week 5 and beyond, highlighting the Bills, who are covering the spread by more than a touchdown per game.

Meanwhile, Buffalo-Seattle under the total is a match for our own Nick Giffen’s Luck Rankings. (Check out all of his Week 8 picks here.)

To round out the stance on Bills vs. Seahawks under, our High Winds PRO System (profitable over the long haul in weather games) notes significant weather elements Sunday in Seattle.

Pick: Seahawks +3 & Under 45.5

Betting Trends to Know

How to Watch: Time, Channel, Streaming

Location:Lumen Field
Date:Sunday, Oct. 27
Kickoff Time:4:05 p.m. ET
TV / Streaming:FOX / YouTube TV

Seahawks vs. Bills is scheduled for a 4:05 p.m. ET start time, live from Lumen Field in Seattle, WA, on Sunday, Oct. 27. The game is broadcasted live by FOX and is streaming on YouTube TV.

NFL Weather

Get the latest coverage on NFL Weather.

About the Author
Alex began his career as a freelancer before becoming a columnist, reporter, and breaking news writer for FanRag Sports, and later the leading gambling writer at theScore. He joined the Action Network as a senior news editor, handling breaking news and the sports betting market's reactions. Alex also works on Action Network’s PRO projections, transforming subscription-based models into user-friendly content.

Follow Alex Kolodziej @KolodziejAlex on Twitter/X.

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