Buffalo Bills Odds

Buffalo Bills Odds, Bet Types, and Team History

The Buffalo Bills have become a yearly AFC contender thanks to the presence of one of the game's best signal callers, Josh Allen. Allen and head coach Sean McDermott won't have their best offensive weapon at their disposal in 2024-25, though, as Stefon Diggs was traded to the Houston Texans in the offseason.

In a conference featuring the Kansas City Chiefs and Baltimore Ravens and in a tough AFC East, it won't be an easy road for Buffalo. The Bills have been beaten by Patrick Mahomes and the Chiefs in three of the last four postseasons.

Regardless, here's how to bet the Bills in 2024-25.

Betting on the Buffalo Bills

Here are the most popular ways to bet on the Bills this season:

• Point Spread
• Moneyline
• Over/Unders
• Props
• Future Odds

Bills Spread

Betting point spreads are wagers based on the expectation that a team will win or lose by a certain number of points. Here's an example of how the spread works using the Bills' Week 1 game against the Arizona Cardinals. 

• Bills -7 (-105)
• Cardinals +7 (-115)

In this situation, the Cardinals are 7-point underdogs against the Bills. If Buffalo wins the game by eight or more points, a $105 wager on the Bills would come with a payout of $100. If Arizona won the game outright or lost by six points or less, a $115 wager would net $100. If the Bills won by seven points, that would net a push. 

Bills Moneyline

Buffalo was 11-6 against the moneyline on its way to a division title in 2023-24. But it also lost as heavy moneyline favorites multiple times, including as over -400 favorites against the Patriots on the road. Transitioning to this season, here's an example of a Bills moneyline bet.

• Bills -330
• Cardinals +265

The minus (-) and plus (+) signs distinguish the favorite from the underdog, making Bills the favorite in this scenario. Odds can be understood more clearly if you think in terms of $100 increments. A wager on the Bills odds would mean every $330 bet nets $100. And it's the opposite for underdogs: Here the Cardinals moneyline was set at +265, meaning a $100 wager would profit $265.

Moneylines are also commonly used when making parlays, which are multiple bets tied into one. Let’s say you bet the Bills moneyline and a 7-point spread. Buffalo would need to win by eight points or more for that bet to be successful. The risk is greater, but so is the reward with increased odds. Use our Odds Calculator to calculate any bet amount or conversion.

Bills Over/Under

Over/under, also called point total, is a wager placed on the combined scoring of a single game. Bookmakers come up with a number and you can either bet the over or the under. Here’s how it works:

The Bills play the Cardinals and the over/under is set at 48.5 points. A wager on the over would require Buffalo and Arizona to score 49 total points or more to win. Betting the under is an expectation that the two teams would score 48 points or fewer.

The Bills had an 8-11 over/under record in 2023 and averaged 26.5 points per game (6th in NFL).

Bills Prop Bets

Player props are wagers on a single player, and they're tied to a single stat found in the box score for a game or even the whole season. These are among the most fun to bet on, especially if you're already playing fantasy football and like the player-specific focus it offers. Check out a hypothetical example below:

• Over/Under: Josh Allen passing yards: 3,750

In this example, a bettor will wager on whether or not Allen will throw for more or less than 3,750 yards over the course of the season.

Bills Future Odds

A futures bet is a wager that will decided based on a result that takes place later in the season. Future bets can be made on both team and individual player outcomes. Some examples of popular futures bets include:

• Buffalo Bills odds to win the AFC East
• Buffalo Bill odds to win the AFC
• Buffalo Bill odds to win the Super Bowl

Because NFL futures are so hard to predict, bettors can expect highly favorable odds with sizeable payouts should they win.

Weather for Bills Games

Keep track of the conditions for Bills games by checking out our NFL weather page.

How to Bet on the Buffalo Bills

New Yorkers and Buffalo Bills fans alike have a great variety of sportsbooks to choose from to place their online wagers. Here are a few top books that offer terrific new registration offers through the Action Network.

Caesars Sportsbook

Caesars Sportsbook is one of two official sports betting partners of the Buffalo Bills. Read our Caesars review for more information about Caesars and instructions on how to sign up.

BetMGM Sportsbook

BetMGM is another popular and growing sportsbook throughout New York. BetMGM offers new and veteran bettors alike a terrific betting experience with a simple and easy-to-use design. Take a look at our full BetMGM review to discover why this is a great sportsbook option.