Cardinals vs Bills Weather, Odds, NFL Sunday Forecast for Week 1

Cardinals vs Bills Weather, Odds, NFL Sunday Forecast for Week 1 article feature image
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A general view of Highmark Stadium (Photo by Timothy T Ludwig/Getty Images)

The Cardinals vs. Bills weather could become a crucial factor for bettors this Sunday in Week 1.

Weather conditions can be notoriously tricky to navigate, but that's where our PRO Systems come into play. Sunday's Cardinals vs. Bills game has been flagged because there's enough significant data in Sunday's HighMark Stadium forecast to make an informed pick.

It's a season opener for both teams, featuring dynamic dual-threat quarterbacks: Kyler Murray for the Cardinals and Josh Allen for the Bills.

Also, if you’re interested in using weather to make your NFL picks, another game fits Sunday's criteria as well.


Cardinals vs. Bills Weather, Odds, NFL Sunday Forecast for Week 1

Cardinals Logo
Sunday, Sep 8
1 p.m. ET
CBS
Bills Logo
Cardinals Odds
SpreadTotalMoneyline
+6.5
-110
47.5
-102o / -120u
+240
Bills Odds
SpreadTotalMoneyline
-6.5
-110
47.5
-102o / -120u
-295
Odds via FanDuel. Get up-to-the-minute NFL odds here.
FanDuel Logo

In terms of betting odds, the Bills are favored by 6.5 points with the over/under set at 47.5.

The best strategy for bettors in this instance is to focus on the over/under.

Let's dive into why you should consider the weather before placing your bets for the Bills vs. Cardinals game.