NFL Odds, Picks, Predictions for Every Game: Week 6 NFL Schedule

NFL Odds, Picks, Predictions for Every Game: Week 6 NFL Schedule article feature image
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Getty Images. Pictured: A close-up of the NFL logo on a football.

Our experts have taken a look up and down the NFL Week 6 schedule, and they've come away with their best bets for every game.

The tightest spread at the moment is in Colts vs. Titans and Bills vs. Jets tomorrow night, where the Titans and Bills are each 2.5-point favorites. There are a couple other games at the key number of 3 currently, so we could see some movement there. The biggest spread is in Browns vs. Eagles, as Philadelphia is an 8.5-point favorite against Cleveland (Eagles -8.5).

The highest over/under is in Lions vs. Cowboys on Sunday afternoon at 52.5 points, and the lowest total is the over/under 35.5 in Chargers vs. Broncos.

But those are just the superlatives. Let's get to the Week 6 NFL odds, our expert picks, and NFL predictions for every game.

Week 6 NFL Predictions

NFL Odds, Spreads Today

  • Commanders vs. Ravens Spread: Ravens -6.5
  • Texans vs. Patriots Spread: Texans -6.5
  • Browns vs. Eagles Spread: Eagles -8.5
  • Colts vs. Titans Spread: Titans -2.5
  • Cardinals vs. Packers Spread: Packers -5.5
  • Buccaneers vs. Saints Spread: Bucs -3.5
  • Steelers vs. Raiders Spread: Steelers -3
  • Chargers vs. Broncos Spread: Chargers -3
  • Lions vs. Cowboys Spread: Lions -3
  • Falcons vs. Panthers Spread: Falcons -6
  • Bengals vs. Giants Spread: Bengals -3.5
  • Bills vs. Jets Spread: Bills -2.5

Week 6 NFL Schedule

Washington Commanders at Baltimore Ravens

Commanders Logo
Sunday, Oct 13
1 p.m. ET
CBS
Ravens Logo
Commanders Odds
SpreadTotalMoneyline
+6.5
-108
51.5
-110o / -110u
+245
Ravens Odds
SpreadTotalMoneyline
-6.5
-112
51.5
-110o / -110u
-285
Odds via DraftKings. Get up-to-the-minute NFL odds here.
DraftKings Logo
  • Commanders vs. Ravens Spread: Ravens -6.5
  • Commanders vs. Ravens Over/Under: 51.5 points
  • Commanders vs. Ravens Moneyline: Ravens -300, Commanders +240
  • Commanders vs Ravens Pick, Prediction: Under the total

Houston Texans at New England Patriots

Texans Logo
Sunday, Oct 13
1 p.m. ET
CBS
Patriots Logo
Texans Odds
SpreadTotalMoneyline
-6.5
-110
37.5
-110o / -110u
-265
Patriots Odds
SpreadTotalMoneyline
+6.5
-110
37.5
-110o / -110u
+225
Odds via DraftKings. Get up-to-the-minute NFL odds here.
DraftKings Logo
  • Texans vs. Patriots Spread: Texans -6.5
  • Texans vs. Patriots Over/Under: 37.5 points
  • Texans vs. Patriots Moneyline: Texans -300, Patriots +240
  • Texans vs. Patriots Pick, Prediction: Patriots to cover the spread

Cleveland Browns at Philadelphia Eagles

Browns Logo
Sunday, Oct 13
1 p.m. ET
FOX
Eagles Logo
Browns Odds
SpreadTotalMoneyline
+8.5
-112
42.5
-108o / -112u
+350
Eagles Odds
SpreadTotalMoneyline
-8.5
-108
42.5
-108o / -112u
-425
Odds via DraftKings. Get up-to-the-minute NFL odds here.
DraftKings Logo
  • Browns vs. Eagles Spread: Eagles -8.5
  • Browns vs. Eagles Over/Under: 42.5 points
  • Browns vs. Eagles Moneyline: Eagles -427, Browns +335
  • Browns vs. Eagles Pick, Prediction: Eagles to cover the 1H spread

Indianapolis Colts at Tennessee Titans

Colts Logo
Sunday, Oct 13
1 p.m. ET
CBS
Titans Logo
Colts Odds
SpreadTotalMoneyline
+3
-115
43
-108o / -112u
+125
Titans Odds
SpreadTotalMoneyline
-3
-105
43
-108o / -112u
-148
Odds via DraftKings. Get up-to-the-minute NFL odds here.
DraftKings Logo
  • Colts vs. Titans Spread: Titans -2.5
  • Colts vs. Titans Over/Under: 43 points
  • Colts vs. Titans Moneyline: Titans -150, Colts +125
  • Colts vs. Titans Pick, Prediction: Titans to cover the spread

Arizona Cardinals at Green Bay Packers

Cardinals Logo
Sunday, Oct 13
1 p.m. ET
FOX
Packers Logo
Cardinals Odds
SpreadTotalMoneyline
+5.5
-110
47
-112o / -108u
+195
Packers Odds
SpreadTotalMoneyline
-5.5
-110
47
-112o / -108u
-230
Odds via DraftKings. Get up-to-the-minute NFL odds here.
DraftKings Logo
  • Cardinals vs. Packers Spread: Packers -5.5
  • Cardinals vs. Packers Over/Under: 47.5 points
  • Cardinals vs. Packers Moneyline: Packers -245, Cardinals +200
  • Cardinals vs. Packers Pick, Prediction: Under the total

Tampa Bay Buccaneers at New Orleans Saints

Buccaneers Logo
Sunday, Oct 13
1 p.m. ET
FOX
Saints Logo
Buccaneers Odds
SpreadTotalMoneyline
-3.5
-108
42.5
-108o / -112u
-170
Saints Odds
SpreadTotalMoneyline
+3.5
-112
42.5
-108o / -112u
+145
Odds via DraftKings. Get up-to-the-minute NFL odds here.
DraftKings Logo
  • Buccaneers vs. Saints Spread: Bucs -3.5
  • Buccaneers vs. Saints Over/Under: 42.5 points
  • Buccaneers vs. Saints Moneyline: Bucs -180, Saints +150
  • Buccaneers vs. Saints Pick, Prediction: Saints to cover the spread

Pittsburgh Steelers at Las Vegas Raiders

Steelers Logo
Sunday, Oct 13
4:05 p.m. ET
CBS
Raiders Logo
Steelers Odds
SpreadTotalMoneyline
-3
-118
36.5
-108o / -112u
-170
Raiders Odds
SpreadTotalMoneyline
+3
-102
36.5
-108o / -112u
+145
Odds via DraftKings. Get up-to-the-minute NFL odds here.
DraftKings Logo
  • Steelers vs. Raiders Spread: Steelers -3
  • Steelers vs. Raiders Over/Under: 36.5 points
  • Steelers vs. Raiders Moneyline: Steelers -175, Raiders +145
  • Steelers vs. Raiders Pick, Prediction: Steelers to cover the spread

Los Angeles Chargers at Denver Broncos

Chargers Logo
Sunday, Oct 13
4:05 p.m. ET
CBS
Broncos Logo
Chargers Odds
SpreadTotalMoneyline
-3
-105
35.5
-112o / -108u
-145
Broncos Odds
SpreadTotalMoneyline
+3
-115
35.5
-112o / -108u
+125
Odds via DraftKings. Get up-to-the-minute NFL odds here.
DraftKings Logo
  • Chargers vs. Broncos Spread: Chargers -3
  • Chargers vs. Broncos Over/Under: 35.5 points
  • Chargers vs. Broncos Moneyline: Chargers -155, Broncos +130
  • Chargers vs. Broncos Pick, Prediction: Broncos to cover the spread

Detroit Lions at Dallas Cowboys

Lions Logo
Sunday, Oct 13
4:25 p.m. ET
FOX
Cowboys Logo
Lions Odds
SpreadTotalMoneyline
-3.5
-102
52.5
-110o / -110u
-170
Cowboys Odds
SpreadTotalMoneyline
+3.5
-118
52.5
-110o / -110u
+145
Odds via DraftKings. Get up-to-the-minute NFL odds here.
DraftKings Logo
  • Lions vs. Cowboys Spread: Lions -3
  • Lions vs. Cowboys Over/Under: 52.5 points
  • Lions vs. Cowboys Moneyline: Lions -170, Cowboys +142
  • Lions vs. Cowboys Pick, Prediction: Cowboys to cover the spread

Atlanta Falcons at Carolina Panthers

Falcons Logo
Sunday, Oct 13
4:25 p.m. ET
FOX
Panthers Logo
Falcons Odds
SpreadTotalMoneyline
-6
-108
46
-112o / -108u
-250
Panthers Odds
SpreadTotalMoneyline
+6
-112
46
-112o / -108u
+210
Odds via DraftKings. Get up-to-the-minute NFL odds here.
DraftKings Logo
  • Falcons vs. Panthers Spread: Falcons -6
  • Falcons vs. Panthers Over/Under: 46.5 points
  • Falcons vs. Panthers Moneyline: Falcons -267, Panthers +215
  • Falcons vs. Panthers Pick, Prediction: Falcons 1H over

Sunday Night Football: Cincinnati Bengals at New York Giants

Bengals Logo
Sunday, Oct 13
8:20 p.m. ET
NBC
Giants Logo
Bengals Odds
SpreadTotalMoneyline
-3.5
-112
47
-108o / -112u
-185
Giants Odds
SpreadTotalMoneyline
+3.5
-108
47
-108o / -112u
+155
Odds via DraftKings. Get up-to-the-minute NFL odds here.
DraftKings Logo
  • Bengals vs. Giants Spread: Bengals -3.5
  • Bengals vs. Giants Over/Under: 47 points
  • Bengals vs. Giants Moneyline: Bengals -190, Giants +155
  • Bengals vs. Giants Pick, Prediction: Under the total

Monday Night Football: Buffalo Bills at New York Jets

Bills Logo
Monday, Oct 14
8:15 p.m. ET
ESPN
Jets Logo
Bills Odds
SpreadTotalMoneyline
-2
-110
41
-108o / -112u
-125
Jets Odds
SpreadTotalMoneyline
+2
-110
41
-108o / -112u
+110
Odds via DraftKings. Get up-to-the-minute NFL odds here.
DraftKings Logo
  • Bills vs. Jets Spread: Bills -2.5
  • Bills vs. Jets Over/Under: 41 points
  • Bills vs. Jets Moneyline: Bills -132, Jets +112
  • Bills vs. Jets Pick, Prediction: Jets to cover the spread

Teams on Bye in Week 6

Kansas City Chiefs, Los Angeles Rams, Miami Dolphins, Minnesota Vikings

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