NFL Odds, Picks, Predictions for Every Game: Week 5 Schedule

Action Network Staff

Updated:

Oct 06, 2024, 11:07 AM EDT

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Getty Images. Pictured: An NFL football on the field before a game.

Our experts have taken a look up and down the NFL Week 5 schedule, and they've come away with their best bets for every game.

The tightest spread at the moment is in Bills vs. Texans, where the Texans are currently just 1-point favorites over the Bills (Texans -1). The biggest spread is in Cardinals vs. 49ers, as San Francisco is a 7.5-point favorite (49ers -7.5).

The highest over/under on the board at the moment is 49 points, which is the total in both Cardinals vs. 49ers and Packers vs. Rams, while the lowest total is the over/under 36 in both Dolphins vs. Patriots and Raiders vs. Broncos.

But those are just the superlatives. Let's get to the Week 5 NFL odds, the full schedule, our expert picks, and NFL predictions for every game.

Week 5 NFL Predictions

Dolphins vs. Patriots Prediction: Under the total
Panthers vs. Bears Prediction: Panthers to cover the spread
Colts vs. Jaguars Prediction: Jaguars to cover the spread
Bills vs. Texans Prediction: Texans to cover the spread
Ravens vs. Bengals Prediction: Bengals to cover the spread
Browns vs. Commanders Prediction: Browns to cover the spread
Raiders vs. Broncos Prediction: Broncos to cover the spread
Cardinals vs. 49ers Prediction: Cardinals to cover the spread
Giants vs. Seahawks Prediction: Giants to cover the spread
Packers vs. Rams Prediction: Rams to cover the spread
Cowboys vs. Steelers Prediction: Steelers to cover the spread
Saints vs. Chiefs Prediction: Under the total

NFL Odds, Spreads Today

Dolphins vs. Patriots Spread: Dolphins -1.5
Panthers vs. Bears Spread: Bears -4
Colts vs. Jaguars Spread: Jaguars -3.5
Bills vs. Texans Spread: Texans -1
Ravens vs. Bengals Spread: Ravens -2.5
Browns vs. Commanders Spread: Commanders -3
Raiders vs. Broncos Spread: Broncos -3
Cardinals vs. 49ers Spread: 49ers -7.5
Giants vs. Seahawks Spread: Seahawks -7
Packers vs. Rams Spread: Packers -3
Cowboys vs. Steelers Spread: Steelers -2.5
Saints vs. Chiefs Spread: Chiefs -5.5

Week 5 NFL Schedule

New York Jets at Minnesota Vikings

Sunday, Oct 6

9:30 a.m. ET

NFL Network

Jets Odds
Spread	Total	Moneyline
+2.5 -105	41.5 -108o / -112u	+124

Vikings Odds
Spread	Total	Moneyline
-2.5 -115	41.5 -108o / -112u	-135

Odds via DraftKings. Get up-to-the-minute NFL odds here.

Jets vs. Vikings Spread: Vikings -2.5
Jets vs. Vikings Over/Under: 41.5 points
Jets vs. Vikings Moneyline: Vikings -145, Jets +120
Jets vs. Vikings Pick, Prediction: Jets to cover the spread

Miami Dolphins at New England Patriots

Sunday, Oct 6

1 p.m. ET

FOX

Dolphins Odds
Spread	Total	Moneyline
-1 -112	35.5 -108o / -112u	-115

Patriots Odds
Spread	Total	Moneyline
+1 -108	35.5 -108o / -112u	+100

Odds via DraftKings. Get up-to-the-minute NFL odds here.

Dolphins vs. Patriots Spread: Dolphins -1
Dolphins vs. Patriots Over/Under: 35.5 points
Dolphins vs. Patriots Moneyline: Dolphins -118, Patriots -102
Dolphins vs. Patriots Pick, Prediction: Under the total

Carolina Panthers at Chicago Bears

Sunday, Oct 6

1 p.m. ET

FOX

Panthers Odds
Spread	Total	Moneyline
+4 -110	41 -108o / -112u	+155

Bears Odds
Spread	Total	Moneyline
-4 -110	41 -108o / -112u	-180

Odds via DraftKings. Get up-to-the-minute NFL odds here.

Panthers vs. Bears Spread: Bears -4
Panthers vs. Bears Over/Under: 41 points
Panthers vs. Bears Moneyline: Bears -200, Panthers +165
Panthers vs. Bears Pick, Prediction: Panthers to cover the spread

Indianapolis Colts at Jacksonville Jaguars

Sunday, Oct 6

1 p.m. ET

CBS

Colts Odds
Spread	Total	Moneyline
+3.5 -118	45 -112o / -108u	+142

Jaguars Odds
Spread	Total	Moneyline
-3.5 -102	45 -112o / -108u	-165

Odds via DraftKings. Get up-to-the-minute NFL odds here.

Colts vs. Jaguars Spread: Jaguars -3.5
Colts vs. Jaguars Over/Under: 45.5 points
Colts vs. Jaguars Moneyline: Jaguars -175, Colts +145
Colts vs. Jaguars Pick, Prediction: Jaguars to cover the spread

Buffalo Bills at Houston Texans

Sunday, Oct 6

1 p.m. ET

CBS

Bills Odds
Spread	Total	Moneyline
+1 -110	47 -108o / -112u	+100

Texans Odds
Spread	Total	Moneyline
-1 -110	47 -108o / -112u	-115

Odds via DraftKings. Get up-to-the-minute NFL odds here.

Bills vs. Texans Spread: Texans -1
Bills vs. Texans Over/Under: 47 points
Bills vs. Texans Moneyline: Texans -120, Bills +100
Bills vs. Texans Pick, Prediction: Texans to cover the spread

Baltimore Ravens at Cincinnati Bengals

Sunday, Oct 6

1 p.m. ET

CBS

Ravens Odds
Spread	Total	Moneyline
-2.5 -108	48.5 -110o / -110u	-130

Bengals Odds
Spread	Total	Moneyline
+2.5 -112	48.5 -110o / -110u	+115

Odds via DraftKings. Get up-to-the-minute NFL odds here.

Ravens vs. Bengals Spread: Ravens -2.5
Ravens vs. Bengals Over/Under: 48.5 points
Ravens vs. Bengals Moneyline: Ravens -135, Bengals +115
Ravens vs. Bengals Pick, Prediction: Bengals to cover the spread

Cleveland Browns at Washington Commanders

Sunday, Oct 6

1 p.m. ET

FOX

Browns Odds
Spread	Total	Moneyline
+3 -115	43.5 -112o / -108u	+125

Commanders Odds
Spread	Total	Moneyline
-3 -105	43.5 -112o / -108u	-145

Odds via DraftKings. Get up-to-the-minute NFL odds here.

Browns vs. Commanders Spread: Commanders -3
Browns vs. Commanders Over/Under: 43.5 points
Browns vs. Commanders Moneyline: Commanders -150, Browns +125
Browns vs. Commanders Pick, Prediction: Browns to cover the spread

Las Vegas Raiders at Denver Broncos

Sunday, Oct 6

4:05 p.m. ET

FOX

Raiders Odds
Spread	Total	Moneyline
+2.5 +100	35.5 -108o / -112u	+124

Broncos Odds
Spread	Total	Moneyline
-2.5 -120	35.5 -108o / -112u	-140

Odds via DraftKings. Get up-to-the-minute NFL odds here.

Raiders vs. Broncos Spread: Broncos -2.5
Raiders vs. Broncos Over/Under: 35.5 points
Raiders vs. Broncos Moneyline: Broncos -150, Raiders +125
Raiders vs. Broncos Pick, Prediction: Broncos to cover the spread

Arizona Cardinals at San Francisco 49ers

Sunday, Oct 6

4:05 p.m. ET

FOX

Cardinals Odds
Spread	Total	Moneyline
+7 -108	48.5 -110o / -110u	+280

49ers Odds
Spread	Total	Moneyline
-7 -112	48.5 -110o / -110u	-330

Odds via DraftKings. Get up-to-the-minute NFL odds here.

Cardinals vs. 49ers Spread: 49ers -7
Cardinals vs. 49ers Over/Under: 49 points
Cardinals vs. 49ers Moneyline: 49ers -350, Cardinals +275
Cardinals vs. 49ers Pick, Prediction: Cardinals to cover the spread

New York Giants at Seattle Seahawks

Sunday, Oct 6

4:25 p.m. ET

CBS

Giants Odds
Spread	Total	Moneyline
+7 -110	42.5 -112o / -108u	+270

Seahawks Odds
Spread	Total	Moneyline
-7 -110	42.5 -112o / -108u	-320

Odds via DraftKings. Get up-to-the-minute NFL odds here.

Giants vs. Seahawks Spread: Seahawks -7
Giants vs. Seahawks Over/Under: 42.5 points
Giants vs. Seahawks Moneyline: Seahawks -330, Giants +265
Giants vs. Seahawks Pick, Prediction: Giants to cover the spread

Green Bay Packers at Los Angeles Rams

Sunday, Oct 6

4:25 p.m. ET

CBS

Packers Odds
Spread	Total	Moneyline
-3 -120	49 -110o / -110u	-162

Rams Odds
Spread	Total	Moneyline
+3 +100	49 -110o / -110u	+140

Odds via DraftKings. Get up-to-the-minute NFL odds here.

Packers vs. Rams Spread: Packers -3
Packers vs. Rams Over/Under: 49 points
Packers vs. Rams Moneyline: Packers -165, Rams +140
Packers vs. Rams Pick, Prediction: Rams to cover the spread

Sunday Night Football: Dallas Cowboys at Pittsburgh Steelers

Sunday, Oct 6

8:20 p.m. ET

NBC

Cowboys Odds
Spread	Total	Moneyline
+3 -115	44 -108o / -112u	+125

Steelers Odds
Spread	Total	Moneyline
-3 -105	44 -108o / -112u	-145

Odds via DraftKings. Get up-to-the-minute NFL odds here.

Cowboys vs. Steelers Spread: Steelers -2.5
Cowboys vs. Steelers Over/Under: 44 points
Cowboys vs. Steelers Moneyline: Steelers -150, Cowboys +125
Cowboys vs. Steelers Pick, Prediction: Steelers to cover the spread

Monday Night Football: New Orleans Saints at Kansas City Chiefs

Monday, Oct 7

8:15 p.m. ET

ESPN

Saints Odds
Spread	Total	Moneyline
+5.5 -108	43 -112o / -108u	+210

Chiefs Odds
Spread	Total	Moneyline
-5.5 -112	43 -112o / -108u	-245

Odds via DraftKings. Get up-to-the-minute NFL odds here.

Saints vs. Chiefs Spread: Chiefs -5.5
Cowboys vs. Steelers Over/Under: 43 points
Cowboys vs. Steelers Moneyline: Chiefs -250, Saints +200
Saints vs. Chiefs Pick, Prediction: Under the total

Action Network Staff

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