Week 4 NFL Odds: Spreads, Totals & Opening Lines For Every Game

Week 4 NFL Odds: Spreads, Totals & Opening Lines For Every Game article feature image
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Chris Graythen/Getty Images. Pictured: Tom Brady

Heading into Sunday Night Football, Week 3 favorites covered at a 8-5 rate while overs also hit at 8-5 rate.

With two primetime games left to play, oddsmakers have already released Week 4 opening lines. We've outlined all the posted spreads and totals available as of Sunday night below.

Week 4 NFL Odds: Spreads & Totals Odds


Odds as of Sunday night and via DraftKings. Get up to a $1,000 sign-up bonus at DraftKings today or see more offers and reviews for the best online sportsbooks.


Broncos at Jets Odds

  • Odds: Broncos -2.5 [Bet Now]
  • Total: 40 [Bet Now]
  • Time: 8:20 p.m. ET on Sept. 17
  • TV Channel: NFL Network

Cardinals at Panthers Odds

  • Odds: Cardinals -4 [Bet Now]
  • Total: 51.5 [Bet Now]
  • Time: 1 p.m. ET on Sept. 20
  • TV Channel: FOX

Ravens at Washington Odds

  • Odds: Ravens -13.5 [Bet Now]
  • Total: N/A
  • Time: 1 p.m. ET on Sept. 20
  • TV Channel: CBS

Browns at Cowboys Odds

Colts at Bears Odds

Jaguars at Bengals Odds

Chargers at Buccaneers Odds

  • Odds: Buccaneers -7 [Bet Now]
  • Total: 45.5 [Bet Now]
  • Time: 1 p.m. ET on Sept. 20
  • TV Channel: CBS
2019-fantasy-football-cheat-sheets-rankings-projections-draft-kit
Michael Reaves/Getty Images. Pictured: Austin Ekeler

Vikings at Texans Odds

Steelers at Titans

  • Odds: Titans -1.5 [Bet Now]
  • Total: 47.5 [Bet Now]
  • Time: 1 p.m. ET on Sept. 20
  • TV Channel: CBS

Seahawks at Dolphins Odds

  • Odds: Seahawks -7 [Bet Now]
  • Total: 54.5 [Bet Now]
  • Time: 1 p.m. ET on Sept. 20
  • TV Channel: FOX

Saints at Lions Odds

  • Odds: N/A
  • Total: N/A
  • Time: 1 p.m. ET on Sept. 20
  • TV Channel: FOX

Check out our new NFL PRO Report, where we highlight factors that provide betting edges — like large wagers, historically profitable betting systems, model projections and expert picks — that when combined with sharp money can powerfully detail the smartest bets on a given slate.

Giants at Rams Odds

  • Odds: Rams -11.5 [Bet Now]
  • Total: 48 [Bet Now]
  • Time: 4:05 p.m. ET on Sept. 20
  • TV Channel: FOX

Bills at Raiders Odds

  • Odds: Bills -2.5 [Bet Now]
  • Total: 49.5 [Bet Now]
  • Time: 4:25 p.m. ET on Sept. 20
  • TV Channel: CBS

Patriots at Chiefs Odds

  • Odds: Chiefs -7 [Bet Now]
  • Total: N/A
  • Time: 4:25 p.m. ET on Sept. 20
  • TV Channel: CBS

Eagles at 49ers Odds

Falcons at Packers Odds

  • Odds: N/A
  • Total: N/A
  • Time: 8:15 p.m. ET on Sept. 21
  • TV Channel: ESPN
About the Author
Katie is the Managing Editor at Action, where she helps oversee the NFL and fantasy football verticals. Her most profitable betting strategy is tailing Sean Koerner (before ultimately losing her winnings on first touchdown props).

Follow Katie Richcreek @katiesrichcreek on Twitter/X.

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