The Ottawa Senators take on the Buffalo Sabres at KeyBank Center in Buffalo. Puck drop is set for 7 p.m. ET and will be streamed on ESPN+.
Ottawa is favored on the moneyline at -150, while Buffalo is an underdog at +125. The total is set at over/under 6.5 goals.
Here is our Senators vs. Sabres prediction and NHL picks for Tuesday, March 25, 2025.
Senators vs. Sabres Prediction
- Pick: Senators ML
Our Ottawa vs. Buffalo best bet is on the Senators to win on the moneyline, with the best odds currently available at FanDuel. For all of your NHL bets, be sure to find the best lines by using our live NHL odds page.
Senators vs. Sabres Odds, Spread, Lines
| Senators Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +158 | 6.5 110o / -134u | -150 |
| Sabres Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -196 | 6.5 110o / -134u | +125 |
- Senators vs. Sabres puck line: Senators -1.5, Sabres +1.5
- Senators vs. Sabres over/under: 6.5 (+110o / -134u)
- Senators vs. Sabres moneyline: Senators -150, Sabres +125
- Senators vs. Sabrespick: Senators ML
Ottawa Senators vs. Buffalo Sabres NHL Preview
The Senators have double revenge and catch the Sabres in a letdown spot.
The Sabres are returning home after upsetting Jets in Winnipeg two days ago. That concluded four straight road games.
Buffalo now is playing for the fourth time in six days while Ottawa hasn't been in action since Saturday.
The Senators are 7-2 in their last nine games and are in great situation here.
Best Bet: Senators Moneyline
