Sharks vs. Sabres Prediction, Odds, Pick for Tuesday, March 4

Sharks vs. Sabres Prediction, Odds, Pick for Tuesday, March 4 article feature image
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Photo by Minas Panagiotakis/Getty Images. Pictured: Alex Tuch

The San Jose Sharks take on the Buffalo Sabres tonight at KeyBank Center in Buffalo. Puck drop is set for 7 p.m. ET and streamed on ESPN+ and Disney+.

The Sabres are favored on the moneyline at -220 odds, while the Sharks are +180 underdogs. The total is set at over/under 6.5 total goals. On the puck line, Sabres -1.5 is +114, while Sharks +1.5 is -135.

Here is my Sabres vs. Sharks prediction and NHL picks for Tuesday, March 4, 2025.

Sharks vs. Sabres Prediction

Quickslip
  • Pick: Over 6.5

My Buffalo vs. San Jose best bet is on over 6.5 total goals scored in the game, with the best odds currently available at BetMGM. For all of your NHL bets, be sure to find the best lines by using our live NHL odds page.

Sharks vs. Sabres Odds, Spread, Lines

Sharks Logo
Tuesday, Mar 4
7 p.m. ET
ESPN+
Sabres Logo
Sharks Odds
SpreadTotalMoneyline
+1.5
-135
6.5
-108o / -112u
+180
Sabres Odds
SpreadTotalMoneyline
-1.5
+114
6.5
-108o / -112u
-218
Odds via DraftKings. Get up-to-the-minute NHL odds here.
DraftKings Logo
  • Sharks vs. Sabres puck line: Sharks +1.5 (-135), Sabres -1.5 (+114)
  • Sharks vs. Sabres over/under: 5.5 (-105o / -115u)
  • Sharks vs. Sabres moneyline: Sharks +180, Sabres -218
  • Sharks vs. Sabrespick: Over 6.5 (-105)

Header First Logo

Sharks vs. Sabres

Betting Pick & Prediction

This is a good spot to take the over with both teams on a back-to-back.

The Sharks go from playing Toronto and Ottawa to Buffalo, while is a much worse defensive opponent. Plus, the Sharks have been creating a decent amount of offense since returning from the break (Top 12 in xGF and high danger chances for since Feb 22nd)

San Jose has found a way to score and give up goals early on the road this season. The Sharks have the third-best first period over record away from home at 21-12.

The Sabres are heading home after losing back-to-back against Montreal. The message in the room from head coach Lindy Ruff before the last Montreal game was to shoot more, and they outshot Montreal 36-20 in a 4-3 OT loss.

At home the Sabres are the best over team in the NHL, going over the total in 20 of their 30 home games this season. One of the big reasons is because the Sabres are scoring the third most goals per game at home this season (3.45)

Vitek Vanecek should draw the start for San Jose after Alexandar Georgiev played on Monday night. Vanecek owns a .866 SV% and 4.53 GAA on the road this year.

Meanwhile, Sabres starter Ukko-Pekka Luukkonen owns a .888 SV% and 3.07 GAA at home this season.

I see this game finishing 5-2 or 5-3 in favor of Buffalo

Pick: Over 6.5

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