White Sox vs. Guardians Odds & Betting Predictions - April 10, 2025

White Sox at Guardians

5:10 pm • CLEG
1 - 6
Starting Pitchers
pitcherteameraw-l
Gavin Williams logoG.WilliamsCleveland Guardians logo3.461-0
Jonathan Cannon logoJ.CannonChicago White Sox logo5.790-2

White Sox at Guardians Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
White Sox
3-10
+1.5
+1.5-105
o7.5+100
+205
Guardians
7-6
u7.5
-1.5-114
u7.5-122
-250
location pinThursday 5:10 p.m.
April 10, 2025
Progressive FieldCleveland
White Sox vs. Guardians Expert Picks
Kyle Just Bets
Kyle Just Bets
Last 30d: 34-31-0 (-1.4u)
G.Williams o1.5 BB (Live)-155
0.65u
Firefighter Bets
Firefighter Bets
Last 30d: 171-177-3 (-11.6u)
S.Kwan o1.5 Hits + Runs + RBIs-140
0.71u
The Propfessor
The Propfessor
Last 30d: 52-33-2 (+15.5u)
G.Williams o5.5 Ks-126
0.79u
MJC Locks
MJC Locks
Last 30d: 13-30-0 (+4.6u)
(CWS) Matt Thaiss o0.5 Batter Walks+145
1.02u
Chris Gimino
Chris Gimino
Last 30d: 214-169-41 (+35.0u)
J.Cannon u3.5 Ks+105
1u
Billy Ward
Billy Ward
Last 30d: 35-34-0 (+7.8u)
Under 0.5 (1st Inn)-125
1.25u
Good to the -135 at Caesars
Picks  Office
Picks Office
Last 30d: 91-68-3 (+19.7u)
CLE -1.5-105
0.95u
White Sox bats ice cold – .198 AVG, .534 OPS in 7-game slide. Just 15 runs in that stretch. Injuries piling up – key hitters hurt. Cannon’s command shaky – 3 BB, 2 HBP in last start. Sox bullpen already has 3 blown saves. Guardians pitching locked in – just 1 ER last 2 games. Pen ranks top 3 in WHIP, opp BA. Gavin Williams got hit by CHW in 2024, but this lineup lacks power. Santana hot – batting .364 last 6, 2 HR. CLE lineup due for bounce after low-run wins. Cannon’s 56.5 GB% sets up for damage on gaps. CLE 6-1 vs CHW in last 7, 4-1 at home. Sox 0-5 on road, worst AL run support away. Guardians eyeing sweep behind hot arms, vets clicking.
Top Shelf Action 🥃
Top Shelf Action 🥃
Last 30d: 351-442-17 (+12.9u)
G.Williams o6.5 Ks+154
0.52u
2.59% ev

White Sox vs. Guardians Previews & Analysis

  • MLB NRFI & YRFI Predictions: +550 for Today article feature image

    MLB NRFI & YRFI Predictions: +550 for Today

    Billy Ward
    Apr 10, 2025 UTC
  • White Sox vs. Guardians: Target Thursday's Total article feature image

    White Sox vs. Guardians: Target Thursday's Total

    Tony Sartori
    Apr 10, 2025 UTC
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Prop Odds Comparison

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Line Movement Tracker

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White Sox vs. Guardians Public Betting Percentages

Away Logo

White Sox

Public

15%

Bets%

85%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Guardians
5-82-23-63-32-4
White Sox
8-55-23-3N/A8-5

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Guardians
6-71-35-43-33-3
White Sox
6-6-14-2-12-4N/A6-6-1

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Guardians
7-64-03-65-12-4
White Sox
3-103-40-6N/A3-10

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Apr 9thCWSW 3-2-1.5 LU 7.5CLE -168
Apr 8thCWSW 1-0-1.5 LU 7.5CLE -202
Apr 6th@LAAL 2-6-1.5 LU 9.5LAA -111
Apr 6th@LAAL 4-10-1.5 LO 9LAA -152
Apr 5th@LAAW 8-6-1.5 WO 8CLE -118

Guardians vs. White Sox Injury Updates

Guardians Injuries

  • Shane Bieber
    P

    Bieber is out with elbow

    Out

  • Slade Cecconi
    P

    Cecconi is out with oblique

    Out

  • John Means
    P

    Means is out with elbow

    Out

  • David Fry
    C

    Fry is out with elbow

    Out

White Sox Injuries

  • Mike Clevinger
    P

    Clevinger is out with back

    Out

  • Josh Rojas
    IF

    Rojas is out with toe

    Out

  • Ky Bush
    P

    Bush is out with elbow

    Out

  • Drew Thorpe
    P

    Thorpe is out with elbow

    Out

White Sox vs. Guardians Box Score
White Sox Player Stats
Projected
PITCHERPCIPKER
Jonathan Cannon logoRJ.Cannon, P1025.166
Bryse Wilson logoRB.Wilson, P191.200
Mike Clevinger logoRM.Clevinger, P6100
HITTERSH-ABRHRRBI
Nick Maton logo1N.Maton, DH1-3100
Andrew Vaughn logo2A.Vaughn, 1B0-4000
Miguel Vargas logo3M.Vargas, 3B0-4000
Matt Thaiss logo4M.Thaiss, C1-3000
Austin Slater logo5A.Slater, RF1-4000
Lenyn Sosa logo6L.Sosa, 2B2-4000
Brooks Baldwin logo7B.Baldwin, LF0-4000
Michael A. Taylor logo8M.Taylor, CF0-2000
Jacob Amaya logo9J.Amaya, SS0-3000
Guardians Player Stats
Projected
PITCHERPCIPKER
Gavin Williams logoRG.Williams, P94571
Jakob Junis logoRJ.Junis, P20210
Joey Cantillo logoLJ.Cantillo, P33240
HITTERSH-ABRHRRBI
Steven Kwan logo1S.Kwan, LF4-5214
Jose Ramirez logo2J.Ramirez, 3B0-4000
Carlos Santana logo3C.Santana, DH0-3000
Kyle Manzardo logo4K.Manzardo, 1B1-4112
Nolan Jones logo5N.Jones, CF1-4000
Jhonkensy Noel logo6J.Noel, RF1-4100
Bo Naylor logo7B.Naylor, C1-3100
Daniel Schneemann logo8D.Schneemann, 2B0-4000
Brayan Rocchio logo9B.Rocchio, SS2-3100

White Sox vs. Guardians Odds Comparison

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White Sox at Guardians Team Totals

MatchupOverUnder
White Sox
3-10
o2.5-121
u2.5-107
Guardians
7-6
o4.5+100
u4.5-129