Clemson vs. Louisville Odds & Betting Predictions - March 15, 2025
Clemson at Louisville
1:30 am • ESPNClemson at Louisville Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
---|---|---|---|---|
![]() Clemson 27-6 | +1 | -2.5-107 | o141.5-115 | -142 |
![]() Louisville 27-7 | u140.5 | +2.5-112 | u141.5-105 | +120 |

Spectrum CenterCharlotte
Clemson vs. Louisville Expert Picks

Gamblers Dream
4d ago
Last 30d: 15-19-0 (+10.8u)
CLEM +10.5 (Live)-112
1u

The Degenerate
4d ago
Last 30d: 76-139-2 (-28.9u)
LOU +1.5-102
0.49u

The Degenerates
5d ago
Last 30d: 87-80-0 (-3.3u)
CLEM -115
1.15u

Charlie Baker
5d ago
Last 30d: 40-32-1 (+6.4u)
CLEM -115
1.5u

Bet Labs
5d ago
Last 30d: 55-41-1 (+12.6u)
LOU +0.5 (1H)-115
1u

Royals Props
5d ago
Last 30d: 52-58-3 (-15.0u)
V.Lakhin o11.5 Pts-120
1u
MGM

Lock & Cash
5d ago
Last 30d: 26-13-0 (+18.5u)
CLEM -115
1.5u

DeadPresPicks
5d ago
Last 30d: 90-75-2 (+5.3u)
CLEM +100
0.55u
Clemson vs. Louisville Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Clemson vs. Louisville Public Betting Percentages
Betting Trends
- Louisville are 4-1 in their last 5 games.
- Louisville are 3-2 in their last 5 games against the spread
- Louisville are 11-3 in their road games against the spread
- The totals have gone OVER in 2 of Louisville' last 5 games
- The totals have gone OVER in 7 of Louisville' 20 last games at home
Matchup History
Against the Spread (ATS) History
overall | home | away | favorite | underdog | |
---|---|---|---|---|---|
![]() | 20-14 | 9-11 | 11-3 | 14-11 | 6-3 |
![]() | 20-13 | 11-8 | 9-5 | 16-11 | 3-2 |
Over/Under History
overall | home o/u | away o/u | favorite o/u | underdog o/u | |
---|---|---|---|---|---|
![]() | 12-22 | 7-13 | 5-9 | 7-18 | 5-4 |
![]() | 17-16 | 11-8 | 6-8 | 14-13 | 3-2 |
Straight-Up (ML) History
overall | home | away | favorite | underdog | |
---|---|---|---|---|---|
![]() | 27-7 | N/A | N/A | 22-3 | 5-4 |
![]() | 27-6 | N/A | N/A | 23-4 | 3-2 |
Last 5 Matchups
Louisville vs. Clemson Injury Updates

Louisville Injuries
- Kasean PryorF
Pryor is out for season with undisclosed
Out for Season
- Chucky HepburnG
Hepburn is questionable with groin
Questionable
- Reyne SmithG
Smith is out with ankle
Out
- Koren JohnsonG
Johnson is out for season with shoulder
Out for Season

Clemson Injuries
- Chase HunterG
Hunter is out for season with hand
Out for Season
- Christian ReevesC
Reeves is questionable with ankle
Questionable
- Asa ThomasF
Thomas is questionable with illness
Questionable
- Ace BucknerG
Buckner is out for season with redshirt
Out for Season
- Del JonesG
Jones is questionable with ankle
Questionable
- Dallas ThomasF
Thomas is out for season with redshirt
Out for Season
Team Stats
27-69 (39%)
Field Goals
24-55 (44%)
14-17 (82%)
Free Throws
22-27 (81%)
5-16 (31%)
3P
6-22 (27%)
33
Rebounds
34
8
Assists
12
9
Turnovers
13
10
Steals
7
2
Blocks
5
22
Fouls
19
Clemson vs. Louisville Odds Comparison
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Clemson at Louisville Team Totals
MatchupOverUnder | ||
---|---|---|
![]() Clemson 27-6 | o71.5-120 | u71.5-110 |
![]() Louisville 27-7 | o69.5-125 | u69.5-105 |