College football odds for Week 5 are up and open for business, and the market's sharpest bettors are already getting involved.
While the early college football Week 5 market isn't as active as recent weeks, there are still two Saturday games that are already being keyed in on by wiseguys:
- No. 22 Wake Forest vs. No. 23 Florida State
- South Alabama vs. Louisiana
Let's look at the two early college football Week 5 picks that the pros are making.
College Football Picks for Week 5
*Odds for Week 5 as of Tuesday morning
Wake Forest vs. Florida State Pick
Oct. 1 | 3:30 p.m. ET | ABC
Coming off an overtime loss to Clemson last weekend, Wake Forest is rewarded with a trip to Tallahassee to take on undefeated Florida State, and it's fair to say that the smart money has been all over the Seminoles to this point.