Georgia vs Alabama, Louisville vs Notre Dame Lead Sharpest Week 5 College Football Picks

Georgia vs Alabama, Louisville vs Notre Dame Lead Sharpest Week 5 College Football Picks article feature image
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: Alabama Crimson Tide starting quarterback Jalen Milroe (4) attempts to evade Georgia Bulldogs defensive back Daylen Everette of Georgia Bulldogs (Photo by David J. Griffin/Icon Sportswire via Getty Images)

The biggest games of Week 5 are popping up everywhere in PRO Systems.

Georgia vs. Alabama, Louisville vs. Notre Dame and Minnesota vs. Michigan lead the sharpest Week 5 college football picks from our backtested models.

Each pick is carefully backed by specific, data-driven PRO Systems designed to maximize your betting success.

Now, let’s delve deeper into each betting prediction, beginning with the game of the year so far in college football.


College Football Week 5 Predictions Against the Spread

PRO Systems are proprietary betting trends or situational angles that account for key historical data to guide better bets.

By using this method, we're making informed decisions about which teams are most likely to cover the spread, based on past performance under similar conditions.

Georgia vs. Alabama Prediction for Week 5

First up is the colossal face-off between Georgia and Alabama.

Kirby Smart's Georgia Bulldogs come in as a -2 favorite, an interesting line given the magnitude of the matchup.

The PRO System known as “Road Streak” pinged with an active pick.

This system illustrates that Power Four teams playing their second-to-fifth consecutive road game tend to be