One of the most compelling matchups in college football Week 5 features Notre Dame hosting Louisville in a Top 25 clash.
With Notre Dame favored (-6) and the over/under at 48, it’s an ACC tilt rife with betting opportunities. Utilizing PRO Systems can tip the scales in our favor, particularly in matchups involving ranked teams.
You can build endless betting trends through PRO Systems.
Our focus here is on the "Ranked Matchups" Action PRO model, which only activates on a pick against the spread whenever — you guessed it — two ranked teams meet.
Enter the Louisville vs. Notre Dame spread, which fits the system like a glove.
Louisville vs Notre Dame Spread Prediction for Week 5
Louisville's flown under the radar are all season. Head coach Jeff Brohm's bunch has covered in all three wins. Saturday's game in South Bend marks the first game in which Louisville has been an underdog all season.
The Fighting Irish, meanwhile, failed to cover yet again last week, though they won at home vs. a MAC squad in Miami (OH).
The "Ranked Matchups" PRO System recommends betting on the