PRO Projections helped cash the biggest spread mismatch of the week Friday. For Sunday's high-profile LSU vs. USC spread, we're employing a unique strategy straight out of our stash of premium angles.
Sunday's LSU vs. USC spread prediction is all about utilizing PRO Systems. One of our college football betting trends, boasting a 58%-win rate, only shows value in games involving two Top 25 teams — just like the September 1, neutral-site clash between No. 13 LSU and No. 23 USC.
LSU promoted quarterbacks coach Joe Sloan and passing game coordinator Cortez Hankton to change the offense around new starting quarterback, Garrett Nussmeier. He succeeds Jayden Daniels and showed some flashes against Wisconsin in the ReliaQuest Bowl.
USC, meanwhile, gears up for its first game as a Big Ten affiliate. Quarterback Miller Moss is the newest engine for the Trojans offense under head coach Lincoln Riley.
USC's schedule ranks as one of the 30 toughest in the nation — and it begins Sunday.
LSU vs USC Spread Pick, Prediction Sunday of College Football Week 1
LSU is the favorite Sunday, hovering around a key number of -4. The spread is -4 to -5 depending on the shop. The LSU vs. USC over/under, meanwhile, is 64.5.
| LSU Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-4 -110 | 64.5 -108o / -112u | -175 |
| USC Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+4 -110 | 64.5 -108o / -112u | +145 |
Who says value's tough to come by in marquee games? Our 58%-winning titled "Ranked Matchups" reveals a clear edge.
This PRO System strategy recommends taking the home team in games where two top-25 college football teams play each other, and the home team is favored