The No. 2 Ohio State Buckeyes (7-1, 4-1 Big Ten) will take on the Purdue Boilermakers (1-7, 0-5) in Ohio Stadium on Saturday, Nov. 9, at 12 p.m. ET on FOX.
The Buckeyes are coming off an impressive 20-13 win on the road over a top-10 Penn State team. On the other side, the Boilermakers have struggled all season and have lost 7 in a row.
Ohio State enters this Week 11 contest as a 38-point favorite on the spread, while the over/under sits at 53.5
So, where's the betting value here? Let's dive into my Ohio State vs Purdue predictions and college football picks for Saturday.
Purdue vs Ohio State Odds
| Purdue Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+37.5 -110 | 54.5 -110o / -110u | +5000 |
| Ohio State Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-37.5 -110 | 54.5 -110o / -110u | -100000 |
- Purdue vs. Ohio State Spread: Purdue +37.5, Ohio State -37.5
- Purdue vs. Ohio State Over/Under: 54.5 Points
- Purdue vs. Ohio State Moneyline: Ohio State ML -100000, Purdue ML +5000
Purdue Boilermakers vs. Ohio State Buckeyes Picks and Predictions
Prediction
My Ohio State vs. Purdue best bet is on the Buckeyes spread, with the best line currently available at bet365, according to our live NCAAF odds page.
Moneyline
PASS
Against the Spread
Purdue vs Ohio State Pick: Ohio State -37.5
Over/Under
PASS
Purdue Boilermakers vs Ohio State Buckeyes College Football Preview
Purdue Boilermakers Betting Preview: Nothing is Going Right
Remember where you were on August 31, 2024?
Purdue was demolishing Indiana State by a score of 49-0, opening the season with a bang and inspiring hope in their entire fan base that surely this year would be different.
Since then, the Boilermakers have been outscored in their next seven games by a total of 295-113, and have lost seven consecutive contests. The impressive part is that it has largely been as ugly as it sounds.
Not only has Purdue lost a lot, but they have lost by a lot! Against elite opponents, Purdue has been beaten by 59 points (Notre Dame), 46 points (Wisconsin), and 35 points (Oregon).
All of those results led Purdue to last week, when the Boilermakers had one final shot at a winnable game, at home, against a Northwestern team with plenty of holes. The Boilers lost in overtime, essentially stamping their fate.
Motivation will be a question here, as there is no bowl game left to play for and all that is left is to play spoiler against an opponent that is better than them in all facets.
The one true sign for optimism mid-season for Purdue was breakout freshman quarterback Ryan Browne, who led the Boilermakers on a furious second-half comeback to make things interesting against Illinois.
Head coach Ryan Walters said it would be a two-quarterback system between Browne and veteran Hudson Card, but the veteran Card threw the ball 37 times to Browne's three last week in the loss to Northwestern.
Purdue ranks outside the top 70 in Rush and Pass Success, as well as Rush and Pass Success allowed. There is no spot on the field that the Boilermakers should feel good about in this game.
Ohio State Buckeyes Betting Preview: Time to Make a Statement
Enter an Ohio State team that feels very good about itself right now.
Ohio State survived on the road against Penn State last week, earning Ryan Day a week off from his many critics concerned with his performances in big games. The main concern here will be a let-down spot, as the Buckeyes know they can take a deep breath and relax a bit.
But I'd argue this is as good a time as any for the Buckeyes to seek out a statement win. Going back a month now, Ohio State has underperformed against the spread in the Oregon loss and a close home win over Nebraska, prior to the Penn State game.
Given that the Bucks are still chasing the Ducks — and are likely playing for College Football Playoff seeding the rest of the way — Ohio State needs some style points, and Ryan Day knows that.
Ohio State has been good this season against opponents that they are favored to beat by 17-38 points, going 3-1 in those four games.
Ohio State ranks inside the top 13 in both Rush and Pass Success, as well as Rush and Pass Success allowed. This is an extremely well-rounded football team with no shortage of talent, and no reason to let up against an overmatched opponent.
Ohio State vs. Purdue Matchup Analysis
Toggle the dropdowns below to hide or show how Ohio State and Purdue match up statistically:
Purdue Offense vs. Ohio State Defense
 | Offense | Defense |  Edge |
| Rush Success | 71 | 13 | |
| Line Yards | 25 | 52 | |
| Pass Success | 101 | 9 | |
| Havoc | 114 | 18 | |
| Finishing Drives | 78 | 1 | |
| Quality Drives | 110 | 5 | |
Ohio State Offense vs. Purdue Defense
| Offense | Defense | Edge |
| Rush Success | 11 | 71 | |
| Line Yards | 9 | 96 | |
| Pass Success | 2 | 129 | |
| Havoc | 32 | 117 | |
| Finishing Drives | 13 | 114 | |
| Quality Drives | 23 | 126 | |
Pace of Play / Other
| | |
| PFF Tackling | 126 | 15 |
| PFF Coverage | 131 | 7 |
| Special Teams SP+ | 101 | 25 |
| Middle 8 | 134 | 48 |
| Seconds per Play | 28.6 (105) | 28.6 (103) |
| Rush Rate | 53% (78) | 55% (55) |
How to Make College Football Picks For My Purdue vs Ohio State Prediction
Last week should have been Purdue's last stand. Given the result in the home loss to Northwestern, this feels like death row for the entire Ryan Walters tenure.
Ohio State has the advantage in every positional matchup, and has plenty still to play for. This feels like a "run the score up" game for the Buckeyes.
Pick: Ohio State -37.5 (-110, bet365) | Bet to -40.5 (-110)
Purdue vs Ohio State Start Time, Channel, Streaming, How To Watch
| Location: | Ohio Stadium, Columbus, OH |
| Date: | Saturday, Nov. 9 |
| Kickoff Time: | 12 p.m. ET |
| TV / Streaming: | FOX |
Purdue vs Ohio State will be played at Ohio Stadium in Columbus, Ohio, on Saturday, Nov. 9 at 12 p.m. ET. You can stream the game live on FOX.
Ohio State vs Purdue Betting Trends
- 81% of bets and 59% of the money are on Purdue to cover the spread
- 81% of bets and 88% of the money are on the over
Betting trends via our live, updating NCAAF public betting & money percentages page.
Ohio State vs Purdue Weather
