Giants vs. 49ers Odds & Betting Predictions - September 22, 2023

Giants at 49ers

12:15 am • Amazon Prime Video

New York Giants

2-12

12 - 30

San Francisco 49ers

6-8

MatchupOpenSpreadTotalMoneyline
Giants 2-12	+10.5-110	o43.5-110	+425
49ers 6-8	-10.5-110	u43.5-114	-575

Friday 12:15 a.m.

September 22, 2023

Levi's StadiumSanta Clara

NYG +14.5 (Live)-126

Feel it in my chicken bones

J.Hyatt o9.5 Rec Yds-120

Have him projected for closer to 2 catches and NYG could be trailing late

P.Campbell u29.5 Rec Yds-120

J.Hyatt o49.5 Rec Yds+1125

0.25u

Sure - catch a bomb rook

I.Hodgins o30.5 Rec Yds-110

1.1u

G.Kittle Anytime TD Scorer+170

2.5u

G.Kittle 2+ TDs+1000

0.5u

G.Kittle 3+ TDs+7400

0.1u

G.Kittle First Touchdown Scorer+800

0.75u

B.Purdy First Touchdown Scorer+1700

0.25u

K.Juszczyk First Touchdown Scorer+3500

0.15u

D.Bellinger First Touchdown Scorer+5000

0.15u

L.Cager First Touchdown Scorer+8000

0.1u

D.Samuel Anytime TD Scorer+110

1.1u

M.Breida o29.5 Rush Yds-125

D.Jones u214.5 Pass Yds-115

0.87u

E.Mitchell Anytime TD Scorer+310

SF u27.5-110

1.1u

Biggest Luck Team Total under of the week. Given on @ActionIsland

G.Kittle u50.5 Rec Yds-110

1.1u

Given on @ActionIsland

B.Purdy u28.5 Pass Att-120

D.Jones o31.5 Pass Att-108

0.93u

M.Breida o2.5 Recs+130

1.3u

X.McKinney o5.5 Tackles + Ast+115

1.15u

Under 43.5-105

G.Kittle u50.5 Rec Yds-120

@nick_giffen

D.Jones u39.5 Rush Yds-110

0.91u

@GDAWG5000

M.Breida u31.5 Rush Yds-115

0.87u

@The_Oddsmaker

Over 43.5-110

0.5u

D.Jones Anytime TD Scorer+260

NYG +10.5-110

J.Hyatt First Touchdown Scorer+9000

0.1u

Hyatt to the 20, 10, TOUCHDOWN!

M.Breida o2.5 Recs+130

1.3u

Giving it at plus money to scare us off

Over 43.5-110

Gut play, somehow the Giants will score

E.Mitchell o29.5 Rush Yds-115

0.87u

@PropBomb

P.Campbell u15.5 Longest Reception-125

0.8u

@The_Oddsmaker

E.Mitchell o29.5 Rush Yds-115

Gave out on Green Dot Daily - More workload. Shanahan admitted “We definitely got get Elijah [Mitchell] in there more” - Short week, blowout potential, avg. 40.2 RushYds/g over in 5/7 single digit carry games - NYG lead the league in explosive rush% - 8.5% plays that go for 15+ yards, and are 2nd in yards before contact

B.Okereke o7.5 Tackles + Ast-145

Full write up: https://www.actionnetwork.com/nfl/nfl-player-props-bet-bobby-okereke-on-thursday-night-football?utm_source=twitter&utm_medium=social&utm_campaign=propbetguy

P.Campbell u15.5 Longest Reception-125

Bet365

D.Samuel First Touchdown Scorer+650

0.5u

My wife gave me this pick while making love

Over 43.5-110

1.1u

POINTS

Under 43.5-110

NYG +10.5-110

3.3u

D.Waller o4.5 Recs+110

0.5u

DK 1:31.

E.Mitchell o74.5 Rush Yds+1075

0.25u

E.Mitchell o49.5 Rush Yds+300

0.25u

Just give me the alts

E.Mitchell Anytime TD Scorer+250

0.5u

E.Mitchell o29.5 Rush Yds-115

0.65u

DraftKings 12:37.

G.Kittle o42.5 Rec Yds-120

E.Mitchell o26.5 Rush Yds-140

0.14u

Resorts World

D.Jones o212.5 Pass Yds-112

$56.00

NYG +10.5-111

1.1u

BetMGM - Projection: +9.5. For more, check out Fantasy Life.

Under 44-110

0.91u

D.Samuel o14.5 Rush Yds-112

$56.00

D.Waller Anytime TD Scorer+270

Biev 🤝 Waller Coke

E.Mitchell o26.5 Rush Yds-113

0.88u

B.Okereke o7.5 Tackles + Ast-125

0.8u

Need my coin back from week 1

NYG +10.5-110

Give SF the trophy if they cover tonight

NYG o16.5-105

1.05u

This hits easily somehow idk tho

E.Mitchell o26.5 Rush Yds-106

Elijah Mitchell Biever

D.Waller o4.5 Recs-110

Biever Ramble POD

T.Hufanga o4.5 Tackles + Ast-148

E.Mitchell o28.5 Rush Yds-115

0.87u

Follow all my picks at FTNBets.com!

Under 44-109

0.92u

Under 44-110

0.91u

@The_Oddsmaker

D.Waller o4.5 Recs+110

Ramble POD 6-0?

SF -10-110

0.91u

SF o13.5 (1H)-140

0.71u

SF o27.5-107

0.93u

Under 44.5-110

T.Hufanga o4.5 Tackles + Ast+100

C.McCaffrey u113.5 Rush + Rec Yds-114

SF -10.5-109

0.92u

D.Samuel Anytime TD Scorer+130

1.3u

Bet at Bet365. Keeping it simple. CMC TD prices nearly unbettable and Deebo can make something out of nothing. Giants blitz a ton and play man coverage at high rate. Should lend itself well to easy dumpoffs to Deebo.

C.McCaffrey u17.5 Rush Att-125

Tailing token here what’s new

D.Slayton o32.5 Rec Yds-110

1.1u

SF -10-110

D.Jones o31.5 Pass Att-108

0.93u

B.Purdy u29.5 Pass Att-114

SF -10-111

0.9u

R.Bell Anytime TD Scorer+2000

Riding with my guy @GDAWG5000 on this

R.Bell Anytime TD Scorer+2000

Bet at Bet365 on 09/19. Down to +850 at FD and +1000 at DK. Aiyuk questionable. Bell played majority of snaps when he was off field. Giants blitz and play man coverage at high rate which plays into Bell getting potential looks.

NYG +10.5-110

$55.00

This one STINKS!

SF -10-109

0.92u

Week 3 Hot Read! 🎙 Niners have won 12 straight, 8 by 13+. Giants keep getting thrashed by great teams, can barely beat awful Cards. Worst run D in NFL last year. Blowout city. Grabbing now cuz Saquon injured + NY OL a disaster so I think this line could rise quickly to 13+ for teaser protection.

Featured Insight
The 49ers have rushed for 2,728 yards since the 2022 season -- sixth-most in NFL. The Giants have allowed 2,737 yards rushing since the 2022 season -- fourth-most in NFL.

TRY FOR FREE

Featured Insight
The Giants have scored on 67% of their drives in late and close games since Week 15 of the 2022 Season -- best in NFL. The 49ers defense has allowed scores on 38% of opponent drives in close and late situations since Week 15 of the 2022 Season -- tied for ninth-worst in NFL.

TRY FOR FREE

McMurphy's Law: Looking Ahead to CFB Week 5
Brett McMurphy•
Sep 27, 2023 UTC
Koerner's Updated Pick'em & Confidence Ratings
Sean Koerner•
Sep 24, 2023 UTC
Action Network's NFL Week 3 Betting Primer (Sunday Update)
Evan Abrams•
Sep 24, 2023 UTC
Our Best Bets for Giants vs. 49ers Tonight
Action Network Staff•
Sep 21, 2023 UTC

See more NFL Coverage

There are no prop projections found for the selected slate. Please check back later.

No props found

NFL Public Betting

49ers are 2-3 in their last 5 games.
49ers are 2-3 in their last 5 games against the spread
49ers are 1-5 in their road games against the spread
The totals have gone OVER in 2 of 49ers' last 5 games
The totals have gone OVER in 4 of 49ers' 8 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
49ers	5-9	4-4	1-5	5-7	0-2
Giants	4-11	2-6	2-4	0-1	4-10

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
49ers	7-7	4-4	3-3	6-6	1-1
Giants	5-10	2-6	3-3	0-1	5-9

Straight-Up (ML) History

	overall	home	away	favorite	underdog
49ers	6-8	N/A	N/A	6-6	0-2
Giants	2-12	N/A	N/A	0-1	2-12

date	opponent	score	spread	over/under	moneyline
Sep 17th	@LA	W 30-23	-7.5 L	O 45	SF -340
Sep 10th	@PIT	W 30-7	-1.5 W	U 41.5	SF -120
Aug 26th	LAC	L 12-23	-7.5 L	U 38.5	LAC -367
Aug 20th	DEN	W 21-20	+3.5 W	O 40	SF +140
Aug 13th	@LV	L 7-34	-4.5 L	O 37	LV -198

Chris Hubbard
T
Hubbard is questionable with knee
Questionable
Graham Gano
K
Gano is questionable with hamstring
Questionable

Aaron Stinnie
G
Stinnie is out with concussion
Out
Greg Stroman
CB
Stroman is out with shoulder
Out
Austin Schlottmann
OL
Schlottmann is questionable with knee
Questionable
Bobby Okereke
LB
Okereke is out with back
Out
Armon Watts
DT
Watts is out with shoulder
Out
Gunner Olszewski
WR
Olszewski is out with groin
Out
Brian Burns
OLB
Burns is questionable with ankle
Questionable
Jon Runyan
G
Runyan is out with ankle
Out
Azeez Ojulari
OLB
Ojulari is out with toe
Out
Patrick Johnson
OLB
Johnson is out with knee
Out
Jason Pinnock
S
Pinnock is questionable with abdomen
Questionable
Kayvon Thibodeaux
OLB
Thibodeaux is questionable with wrist
Questionable
D.J. Davidson
DE
Davidson is doubtful with shoulder
Doubtful
Deonte Banks
CB
Banks is questionable with ribs
Questionable
Dyontae Johnson
LB
Johnson is questionable with ankle
Questionable
Theo Johnson
TE
Johnson is out with foot
Out
Darius Muasau
LB
Muasau is questionable with hamstring
Questionable

Chris Conley
WR
Conley is questionable with knee
Questionable
Jon Feliciano
OL
Feliciano is questionable with knee
Questionable
Trent Williams
T
Williams is out with ankle
Out
Christian McCaffrey
RB
McCaffrey is out with knee
Out
George Odum
S
Odum is out with knee
Out
Dre Greenlaw
LB
Greenlaw is questionable with achilles
Questionable
Nick Bosa
DE
Bosa is questionable with hip
Questionable
Kevin Givens
DE
Givens is questionable with groin
Questionable
Mitch Wishnowsky
P
Wishnowsky is out with back
Out
Brandon Aiyuk
WR
Aiyuk is out with leg
Out
Ben Bartch
OL
Bartch is out with ankle
Out
Khalil Davis
DT
Davis is questionable with knee
Questionable
Jordan Mason
RB
Mason is out with ankle
Out
Robert Beal
DE
Beal is questionable with ankle
Questionable
Darrell Luter
CB
Luter is doubtful with pelvis
Doubtful
Renardo Green
DB
Green is questionable with neck
Questionable
Isaac Guerendo
RB
Guerendo is out with hamstring
Out
Tatum Bethune
LB
Bethune is out with knee
Out

See more NFL Injuries

Giants

Total

49ers

150

Total Yards

441

Total Plays

3.3

Yards Per Play

5.7

Giants

Passing

49ers

137

YDS

310

22/33

Comps/Atts

25/37

3.457

YPA

7.692

0/1

TDs/INTs

2/0

2/16

Sacks/Yards

2/10

Giants

Rushing

49ers

Rush Yards

141

Attempts

2.636

YPC

3.615

TDs

Giants

Turnovers

49ers

Fumbles Lost

Interceptions

Giants

Efficiency

49ers

1/1 100%

Redzone

2/5 40%

3/12 0%

3rd Down

9/16 0%

0/0 0%

4th Down

0/0 0%

Giants

First Downs

49ers

Total

Pass

Rush

Penalty

Giants

Misc

49ers

6/37

Penalties/Yards

6/71

20:50

Possession

39:10

Could not load odds

See more NFL Odds

MatchupOverUnder
Giants 2-12	o15.5-118	u15.5+102
49ers 6-8	o27.5+100	u27.5-122

Giants vs. 49ers Odds & Betting Predictions - September 22, 2023

Giants at 49ers

New York Giants

San Francisco 49ers

Giants at 49ers Odds

Spread, Total, Moneyline

PRO Insights

Giants

49ers

Giants vs. 49ers Previews & Analysis

McMurphy's Law: Looking Ahead to CFB Week 5

Koerner's Updated Pick'em & Confidence Ratings

Action Network's NFL Week 3 Betting Primer (Sunday Update)

Our Best Bets for Giants vs. 49ers Tonight

Giants vs. 49ers Props

Prop Projections

Prop Odds Comparison

Line Movement Tracker

Giants vs. 49ers Public Betting Percentages

Giants

Public

49ers

Bets%

Money%

Betting Trends

Matchup History

Against the Spread (ATS) History

Over/Under History

Straight-Up (ML) History

Last 5 Matchups

Giants vs. 49ers Injury Updates

Giants Injuries

49ers Injuries

Giants vs. 49ers Odds Comparison

Giants at 49ers Team Totals