Twins vs. Guardians Odds & Betting Predictions - April 28, 2025
Twins at Guardians
10:10 pm • MNNTStarting Pitchers
pitcher | team | era | w-l | |
---|---|---|---|---|
![]() | ![]() | 4.15 | 2-1 | |
![]() | ![]() | 5.04 | 2-1 |
Twins at Guardians Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
---|---|---|---|---|
![]() Twins 12-16 | +1.5 | +1.5-198 | o8-117 | +105 |
![]() Guardians 15-12 | u8 | -1.5+167 | u8-105 | -125 |

Progressive FieldCleveland
Twins vs. Guardians Expert Picks

The Degenerate
Last 30d: 110-154-5 (-2.6u)
MIN +0.5 (F5)-140
0.54u

Picks Office
Last 30d: 89-90-4 (-7.2u)
CLE -120
1u
Twins can't win on the road – just 3-10 away this season, batting an ugly .188 with 2.92 R/9. Guardians strong at home – 8-4 record, offense jumps to 4.14 R/9. Gavin Williams (2-0, 2.38 ERA home) thrives at Progressive Field, Twins have lost 7 of last 8 here.
Bailey Ober’s road nightmares – 9.35 ERA, 1.96 WHIP in 8.2 IP away. Guardians bullpen edge – 2.89 ERA vs Twins’ 3.65 bullpen ERA season-long.
Cleveland better vs RHP – .238 AVG compared to Twins’ .232. Guardians’ offense has enough pop to expose Ober's road splits. Twins' brutal trend: 20 losses in last 26 road games. Home momentum, bullpen depth, starting pitching tilt to CLE.

Top Shelf Action 🥃
Last 30d: 495-763-22 (+22.4u)
E.Julien o1.5 Total Bases+185
1.11u
B.Naylor o0.5 Doubles+600
0.2u
K.Manzardo o0.5 Doubles+500
0.2u

Jim Sannes
Last 30d: 30-59-1 (-8.3u)
G.Williams u5.5 Ks-102
0.98u
Have him projected for 5.45 strikeouts. Pitchers in that range for me have gone under 5.5 at a rate around 60%.

Top Shelf Action 🥃
Last 30d: 495-763-22 (+22.4u)
C.Correa o1.5 RBI+650
0.2u
C.Correa o1.5 Hits+275
1.38u

Greg DiNardo
Last 30d: 72-43-1 (+25.7u)
CLE -130
1.3u

Capper Central
Last 30d: 135-90-14 (+30.9u)
CLE PK-107
1.07u

Moneyline Hacks
Last 30d: 135-99-3 (+62.7u)
CLE -120
1u
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Sean Zerillo
Last 30d: 192-193-17 (-1.1u)
CLE -110
0.55u
Bet to -121
Twins vs. Guardians Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Twins vs. Guardians Public Betting Percentages
Betting Trends
- Guardians are 2-3 in their last 5 games.
- Guardians are 2-3 in their last 5 games against the spread
- Guardians are 6-9 in their road games against the spread
- The totals have gone OVER in 3 of Guardians' last 5 games
- The totals have gone OVER in 6 of Guardians' 12 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Guardians vs. Twins Injury Updates

Guardians Injuries
- Shane BieberSP
Bieber is out with elbow
Out
- Slade CecconiSP
Cecconi is out with oblique
Out
- John MeansSP
Means is out with elbow
Out
- Lane ThomasCF
Thomas is out with wrist
Out
- David FryC
Fry is out with elbow
Out

Twins Injuries
- Willi Castro2B
Castro is out with oblique
Out
- Royce Lewis3B
Lewis is out with hamstring
Out
Twins vs. Guardians Box Score

PITCHER | PC | IP | K | ER | |
---|---|---|---|---|---|
![]() | 102 | 7.2 | 2 | 1 | |
![]() | 20 | 1.1 | 1 | 0 |
HITTERS | H-AB | R | HR | RBI |
---|---|---|---|---|
![]() | 1-5 | 1 | 1 | 1 |
![]() | 2-5 | 1 | 0 | 2 |
![]() | 0-0 | 0 | 0 | 0 |
![]() | 2-4 | 1 | 0 | 0 |
![]() | 1-1 | 1 | 0 | 0 |
![]() | 1-1 | 1 | 0 | 0 |
![]() | 1-5 | 1 | 0 | 0 |
![]() | 2-4 | 1 | 0 | 2 |
![]() | 0-1 | 0 | 0 | 0 |
![]() | 0-1 | 0 | 0 | 0 |
![]() | 2-4 | 2 | 1 | 3 |
![]() | 2-5 | 1 | 0 | 1 |
![]() | 3-5 | 1 | 0 | 1 |
![]() | 1-4 | 1 | 0 | 1 |
![]() | 1-4 | 1 | 0 | 1 |

PITCHER | PC | IP | K | ER | |
---|---|---|---|---|---|
![]() | 61 | 2 | 2 | 4 | |
![]() | 31 | 2 | 1 | 0 | |
![]() | 15 | 0.2 | 1 | 0 | |
![]() | 18 | 0.1 | 0 | 2 | |
![]() | 40 | 2 | 1 | 3 | |
![]() | 26 | 2 | 0 | 2 |
HITTERS | H-AB | R | HR | RBI |
---|---|---|---|---|
![]() | 1-3 | 0 | 0 | 0 |
![]() | 1-1 | 0 | 0 | 0 |
![]() | 0-4 | 0 | 0 | 0 |
![]() | 0-4 | 0 | 0 | 0 |
![]() | 1-3 | 0 | 0 | 0 |
![]() | 0-1 | 0 | 0 | 0 |
![]() | 1-4 | 0 | 0 | 0 |
![]() | 1-4 | 0 | 0 | 0 |
![]() | 2-3 | 0 | 0 | 0 |
![]() | 1-4 | 1 | 0 | 0 |
![]() | 0-3 | 0 | 0 | 0 |
![]() | 0-1 | 0 | 0 | 0 |
![]() | 1-4 | 0 | 0 | 1 |
![]() | 0-4 | 0 | 0 | 0 |
Twins vs. Guardians Odds Comparison
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Twins at Guardians Team Totals
MatchupOverUnder | ||
---|---|---|
![]() Twins 12-16 | N/A | N/A |
![]() Guardians 15-12 | N/A | N/A |