One of the most shocking upsets in UFC history came in December of 2021, when Julianna Pena knocked off Amanda Nunes in the bantamweight division as a +700 underdog.
The victory for Pena came as a top-five upset in terms of odds, and while Nunes is favored once again this time around, she's not carrying a -1100 tag again.
Even at a smaller price, bettors aren't ready to back Nunes in her role as challenger.
Opening at -300, Nunes has drawn 30% of the wagers and 30% of the handle, while Pena opened at +230 and has taken 70% of each split at BetMGM.
The co-main event, a bout for the interim flyweight title between Brandon Moreno and Kai Kara-France, is seeing similar action on the underdog.
Unlike the Pena-Nunes fight, the winner of the previous matchup in this head-to-head is favored. Moreno beat Kara-France by decision in 2019, and he's a -225 favorite to get the job done again.
Moreno is tracking 31% of the bets but there is a distinct difference in handle, where the number is 71%. Kara-France is getting 69% of the wagers but only accounts for 29% of the handle.
Everybody loves a Derrick Lewis fight, and he'll be returning to the octagon in this card as well.
Lewis last fought against Tai Tuivasa, who knocked out Lewis in the second round.
This time, he'll be going up against Sergei Pavlovich. Lewis is a slight -140 favorite, amassing 62% of the bets and 33% of the handle.
In the Alex Perez versus Alexandre Pantoja bout, the favored Pantoja is a heavy public favorite to win, getting 75% of the bets and 90% of the handle, moving his odds from -150 to -190.
Finally, Anthony Smith has received 81% of the betting tickets as a +400 underdog to beat Magomed Ankalaev. He accounts for 67% of the handle.