49ers vs. Eagles Pick, Odds
| 49ers Odds | -3 |
| Eagles Odds | +3 |
| Over/Under | 48 |
| Date | Sunday, Dec. 3 |
| Time | 4:25 p.m. ET |
| Channel | FOX |
*49ers vs. Eagles odds as of Sunday morning
The biggest game of the NFL season to this point takes place on Sunday with the San Francisco 49ers visiting the Philadelphia Eagles.
Interestingly, the latest 49ers vs. Eagles odds show San Francisco as a 3-point road favorite, even though Philadelphia sports a gaudy 10-1 record heading into today's game.
As a result, the 49ers vs. Eagles spread has been a popular topic of conversation among mainstream sports media shows, though savvy NFL bettors are spending much more of their attention on the over/under instead.
Continue reading to the see 49ers vs. Eagles pick that the wiseguys are making ahead of Sunday afternoon's kickoff.
49ers vs. Eagles Over/Under Pick
The 49ers vs. Eagles over/under sits at a consensus of 48 as of the time of writing.
